Let the Universe Be Your DM

In tabletop games, the dungeon master, or DM, sets up storylines for characters to play through in order to gain XP points, level up skills, and just, you know, enjoy experiencing. All too often we try to be the DM for our own lives. But the DM isn't a player, and we have a whole universe able and willing to act as our DM...if we can let it. What are some of the obstacles to trusting the universe to be your DM? What are some of the benefits?